מאמרים שפורסמו

2023

Med

Genome-wide association studies and polygenic risk score phenome-wide association studies across complex phenotypes in the human phenotype project

Zachary Levine, Iris Kalka, Dmitry Kolobkov, Tom sharon, Adina Weinberger, Eran Segal

12/28/2023


MACHINE LEARNING FOR HEALTH (ML4H) SYMPOSIUM 2023

A Multimodal Dataset of 21,412 Recorded Nights for Sleep and Respiratory Research

Alon Diament, Maria Gorodetski, Adam Jankelow, Ayya Keshet, Tal Shor, Daphna Weissglas-Volkov, Hagai Rossman, Eran Segal

11/15/2023

2022

SCIENCE ADVANCES

Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients

Thomas Vogl, Iris N Kalka, Shelley Klompus, Sigal Leviatan, Adina Weinberger, Eran Segal

09/23/2022


PLOS ONE

An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents

Daphna Rothschild, Sigal Leviatan, Ariel Hanemann, Yossi Cohen, Omer Weissbrod, Eran Segal 

03/24/2022


NATURE MEDICINE

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

Yeela Talmor-Barkan, Noam Bar, Aviv A Shaul, Nir Shahaf, Anastasia Godneva, Yuval Bussi, Maya Lotan-Pompan, Adina Weinberger, Alon Shechter, Chava Chezar-Azerrad, Ziad Arow, Yoav Hammer, Kanta Chechi, Sofia K Forslund, Sebastien Fromentin, Marc-Emmanuel Dumas, S Dusko Ehrlich, Oluf Pedersen, Ran Kornowski, Eran Segal

02/17/2022

2021

IMMUNITY, INFLAMMATION AND DISEASE

Clinical efficacy of fecal microbial transplantationtreatment in adults with moderate‐to‐severe atopicdermatitis

Mashiah J, Karady T, Fliss-Isakov N, Sprecher E, Slodownik D, Artzi O, Samuelov L, Ellenbogen E, Godneva A, E. Segal, Maharshak N.

12/20/2021


DIABETES CARE

Personalized Postprandial Glucose Response-Targeting Diet Versus Mediterranean Diet for Glycemic Control in Prediabetes

Ben-Yacov O, Godneva A, Rein M, Shilo S, Kolobkov D, Koren N, Cohen Dolev N, Travinsky Shmul T, Wolf BC, Kosower N, Sagiv K, Lotan-Pompan M, Zmora N, Weinberger A, Elinav E, E. Segal

07/23/2021


NATURE MEDICINE

Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota

Vogl T, Klompus S, Leviatan S, Kalka IN, Weinberger A, Wijmenga C, Fu J, Zhernakova A, Weersma RK, E. Segal

07/19/2021


EUROPEAN JOURNAL EPIDEMIOLOGY

Cohort profile: 10K - a large-scale prospective longitudinal study in Israel

7. S. Shilo, N. Bar, A. Keshet, Y. Talmor-Barkan, H. Rossman, A. Godneva, Y. Aviv, Y. Edlitz, L. Reicher, D. Kolobkov, BC. Wolf, M. Lotan-Pompan, K. Levi, O. Cohen, H. Saranga, A. Weinberger, E. Segal

02/23/2021


CELL REPORTS MEDICINE

Potential role of indolelactate and butyrate in multiple sclerosis revealed by integrated microbiome-metabolome analysis

D. Zeevi, T. Korem, A. Godneva, N. Bar, A. Kurilshikov, M. Lotan-Pompan, A. Weinberger, J. Fu, C. Wijmenga, A. Zhernakova, E. Segal

04/20/2021

2020

NATURE

A reference map of potential determinants for the human serum metabolome

N. Bar, T. Korem, O. Weissbrod, D. Zeevi, D. Rothschild, S. Leviatan, N. Kosower, M. Lotan-Pompan, A. Weinberger, CI. Le Roy, C. Menni, A. Visconti, M. Falchi, TD. Spector; IMI DIRECT consortium, J. Adamski, PW. Franks, O. Pedersen, E. Segal

12/03/2020


NATURE

Rich data sets could end costly drug discovery

E. Segal

02/2020


NATURE MEDICINE

Axes of a revolution: challenges and promises of big data in healthcare

S. Shilo, H. Rossman, E. Segal

01/13/2020

2019

NATURE

Potential roles of gut microbiome and metabolites in modulating ALS in mice

12. E. Blacher, S. Bashiardes, H. Shapiro,D. Rothschild, U. Mor1, M. Dori-Bachash, C. Kleimeyer, C. Moresi, Y. Harnik, M. Zur, M. Zabari, R. Ben-Zeev Brik, D. Kviatcovsky, N. Zmora, Y. Cohen, N. Bar, I. Levi, N. Amar, T. Mehlman, A. Brandis, I. Biton, Y. Kuperman, M. Tsoory, L. Alfahel, A. Harmelin, M. Schwartz, A. Israelson, L. Arike, M. Johansson, G.C. Hansson, M. Gotkine, E. Segal*, E. Elinav*

07/22/2019


NATURE

Sub-genomic variation in the gut microbiome associates with host metabolic health

D. Zeevi, T. Korem, A. Godneva, N. Bar, A. Kurilshikov, M. Lotan-Pompan, A. Weinberger, J. Fu, C. Wijmenga, A. Zhernakova, E. Segal

03/27/2019

2018

CELL

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

Jotham Suez, Niv Zmora, Gili Zilberman-Schapira, Uria Mor, Mally Dori-Bachash, Stavros Bashiardes, Maya Zur, Dana Regev-Lehavi, Rotem Ben-Zeev Brik, Sara Federici, Max Horn, Yotam Cohen, Andreas E Moor, David Zeevi, Tal Korem, Eran Kotler, Alon Harmelin, Shalev Itzkovitz, Nitsan Maharshak, Oren Shibolet, Meirav Pevsner-Fischer, Hagit Shapiro, Itai Sharon, Zamir Halpern, Eran Segal, Eran Elinav

09/06/2018


CELL

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

N. Zmora, G. Zilberman-Schapira, J. Suez, U. Mor, M. Dori-Bachash, S. Bashiardes, E. Kotler, M. Zur, D. Regev-Lehavi, R. Ben-Zeev Brik, S. Federici, Y. Cohen, R. Linevsky, D. Rothschild, AE. Moor, S. Ben-Moshe, A. Harmelin, A. Harmelin, S. Itzkovitz, N. Maharshak, O. Shibolet, H. Shapiro, M. Pevsner-Fischer, I. Sharon, Z. Halpern, E. Segal*, E. Elinav*

09/06/2018


NATURE

Environment dominates over host genetics in shaping human gut microbiota

D. Rothschild, O. Weissbrod, E. Barkan, A. Kurilshikov, T. Korem, D. Zeevi, PI. Costea, A. Godneva, IN. Kalka, N. Bar, S. Shilo, D. Lador, AV. Vila, N. Zmora, M. Pevsner-Fischer, D. Israeli, N. Kosower, G. Malka, BC. Wolf, T. Avnit-Sagi, M. Lotan-Pompan, A. Weinberger, Z. Halpern, S. Carmi, J. Fu, Lifelines cohort study, C. Wijmenga, A. Zhernakova, E. Elinav, E. Segal

03/08/2018

2016

NATURE

Persistent microbiome alterations modulate the rate of post-dieting weight regain

C.A. Thaiss, S. Itav, D. Rothschild, M. Meijer, C. Moresi, M. Levy, L. Dohnalová, S. Rozin, Y. Kuperman, I. Biton, A. Harmelin, H. Shapiro, E. Segal*, E. Elinav*

12/22/2016

2015

CELL

Personalized Nutrition by Prediction of Glycemic Responses

D. Zeevi, T. Korem, D. Rothschild, A. Weinberger, N. Zmora, D. Israeli 6, O. Ben-Yacov, D. Lador, T. Avnit-Sagi, M. Lotan-Pompan, J. Suez, J. Ali Mahdi, E. Matot, G. Malka, N. Kosower, M. Rein, G. Zilberman, L. Dohnalova, M. Pevsner-Fischer, R. Bikovsky, Z. Halpern, E. Elinav, E. Segal

11/19/2015


SCIENCE

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples

T. Korem, D. Zeevi, J. Suez, A. Weinberger, T. Avnit-Sagi, M. Pompan-Lotan, E. Matot, G. Jona, A. Harmelin, N. Cohen, A. Sirota-Madi, C.A. Thaiss, M. Pevsner-Fischer, R. Sorek, R. Xavier, E. Elinav, E. Segal

09/04/2015

2014

NATURE

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

J. Suez, T. Korem, D. Zeevi, G. Zilberman-Schapira, C.A. Thaiss, O. Maza, D. Israeli, N. Zmora, S. Gilad, A. Weinberger, Y. Kuperman, A. Harmelin, I. Kolodkin-Gal, H. Shapiro, Z. Halpern, E. Segal*, E. Elinav*

09/17/2014